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AG-CN2-0027)
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Substrate of the horseradish peroxidase enzyme and used as a reagent to amplify immunohistochemical signals
Recombinant Isthmin-1 or overexpression of Ism1 causes a robust increase in GLUT4-dependent glucose uptake in cultured primary murine and immortalized human adipocytes as well as in primary human muscle cells and prevents insulin resistance and hepatic steatosis in a diet-induced obesity mouse model
anti-Polyglutamylation Modification, mAb (GT335) (Biotin) Pack Size:100 µg AG-CN2-0027)Polyglutamylation is a post translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy terminal tubulin tails that participate directly in the binding of many
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